Bone Restore
Throughout life, cells known as osteoblasts construct bone matrix and fill it with calcium. At the same time, osteoclasts work just as busily to tear down and resorb bone. This fine balance is regulated by many factors, including systemic hormones and cytokines. Bone mass reaches its peak by the middle of the third decade of life and plateaus for about ten years, during which time bone turnover is constant, with bone formation approximately equaling bone resorption (1).
As our bodies age, this fine balance is lost. As the relative hormone levels shift in midlife — more drastically in women than in men — the osteoclasts gain the upper hand and bone mass begins to dwindle. Some bone is already being lost by the time women reach menopause, but the rate of loss can increase up to tenfold during the first six years after menopause.
Bone density loss is not just associated with calcium deficiency, but also with an insufficient intake of a host of other nutrients (4-8) including magnesium (9,10) and vitamin D3 (11,12). In order for calcium to help maintain healthy bones, adequate amounts of vitamin D3, zinc (8,13-14), magnesium (15), manganese (7), and other nutrients should be available so that calcium and phosphorus can be incorporated into the bone matrix. Additionally, many forms of calcium are not particularly well absorbed (16-18).
While loss of bone mineral density is more commonly experienced by women, aging men can also have this issue (19). Both men and women may suffer significant deficits of magnesium if they do not supplement. Magnesium is not only needed to maintain strong bones, but it is critical to promoting a healthy vascular system (20-21). In fact, magnesium is critical for facilitating hundreds of enzymatic reactions that our bodies require to maintain optimal health (22-23).
To overcome the impediments that preclude aging adults from achieving optimal calcium status, Life Extension offers a proprietary comprehensive mineral formula called Bone Restore which has been designed to support healthy bone density and strength. Bone Restore provides 1200 milligrams of elemental calcium from three different forms, along with the critically important nutrients magnesium (15), boron (4,24-26), zinc (8,13-14), silicon (27-29), manganes (7), and vitamin D (11,12) needed for healthy bones.
In fact, the boron in this formula, called FruiteX B® OsteoBoron®, is a natural boron/carbohydrate complex, similar to what is found in fruits and vegetables and is more bioavailable than boron citrate. Scientific research has established the beneficial effects of boron on the strength of bones and joints (4,30-33).
One reason why aging people suffer bone loss even though they are taking calcium supplements is that they may not be absorbing enough elemental calcium. Bone Restore provides calcium in capsule form to ensure that it breaks down fully in the digestive tract. Unlike calcium tablets, these capsules burst open within five minutes of swallowing, making the minerals and vitamin D3 immediately available for absorption.
Bone Restore now contains magnesium citrate, which is one of the most absorbable forms of magnesium.
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8. J Int Med Res. 2007 Sep-Oct;35(5):692-5.
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11. J Clin Endocrinol Metab. 2010 Jun;95(6):2630-3.
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20. Congest Heart Fail. 2006 Jan-Feb;12(1):9-13.
21. Br J Sports Med. 2006 Sep;40(9): 773-8.
22. Front Biosci. 2004 May 1;9:1278-93.
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25. Magnes Trace Elem. 1990;9:61-9.
26. Environ Health Perspect. 1994 Nov;102 Suppl 7:59-63.
27. Bone. 2003 Feb;32(2):127-35.
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29. Biol Trace Elem Res. 2008 Nov 27.
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32. Prog Food Nutr Sci. 1993 Oct-Dec;17(4):331-49.
33. Nutr Rev. 2008 Apr;66(4):183-91.
Supplement Facts
Serving Size 5 capsules
Servings Per Container 30
Amount Per Serving
Vitamin D3 (as cholecalciferol) 1000 IU
Calcium (as DimaCal dicalcium malate, TRAACS calcium glycinate chelate, calcium fructoborate) 1200 mg
Magnesium (as magnesium citrate) 100 mg
Zinc 2 mg
Manganese 1 mg
Silicon (from horsetail herb, Equisetum arvense) extract (herb) 5 mg
Boron (calcium fructoborate as patented Fruitex B OsteoBoron) 3 mg
Other ingredients: gelatin, vegetable stearate, maltodextrin.
Contains corn and rice.
Fruitex B® and OsteoBoron are registered trademarks of VDF Futureceuticals, Inc. U.S. patent #5,962,049.
DimaCal® and TRAACS® are registered trademarks of Albion Laboratories, Inc. Malate is covered by U.S. Patent 6,706,904 and patents pending.
Dosage and Use
Take five capsules daily, or as recommended by a healthcare practitioner.
Scientific studies suggest calcium supplementation in divided doses with food in the morning and evening may yield the best results.
Maintaining an optimal vitamin D blood level also helps maximize calcium absorption.
Caution:
Keep out of reach of children.
Do not exceed recommended dose.
Do not purchase if outer seal is broken or damaged.
If you have a bad reaction to product discontinue use immediately.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
