Branched Chain Amino Acids
The branched chain amino acids (BCAAs) L-valine, L-leucine, and L-isoleucine enhance protein synthesis in liver cells and muscle cells. Because they can be oxidized in the cell's mitochondria, the branched chain amino acids may also provide energy and may serve as fuel sources for skeletal muscles during periods of metabolic stress (34-36). As a result, BCAAs have been used with success to support liver function (37-40). A study in 2008 also showed BCAAs supplementation improved insulin resistance and beta cell function as well as energy metabolism and glucose tolerance in certain people (41,42). They are also used by athletes (43-48). A currant mouse study showed that restoring hippocampal BCAA concentrations to normal (by orally supplementing BCAA´s in mice with traumatic brain injury) had the effect of reinstating normal brain function by helping the synapses to function effeciently (49).
References
34. Med Sci Sports Exerc. 1998 Jan;30(1):83-91.
35. J Nutr. 2001 Apr;131(4):1171-6.
36. Surgery. 1981 Aug;90(2):237-43.
37. Clin Gastroenterol Hepatol. 2005 Jul;3(7):705-13.
38. Aliment Pharmacol Ther. 2004 Apr 1;19(7):779-88.
39. Hepatogastoenterology. 2009 Sep-Oct;56(94-95):1491-5.
40. Intern Med. 1998 May;37(5):429-34
41. Int J Mol Med. 2008 Jul;22(1):105-12.
42. Liver Int. 2007 Nov;27(9): 1287-92
43. Nutrition. 1996 Jul-Aug;12(7-8):485-90.
44. J Physiol. 1996 Jun 15;493 ( Pt 3):909-22.
45. Eur J Appl Physiol Occup Physiol. 1994;69(1):26-31.
46. Acta Physiol Scand. 1992 Nov;146(3):293-8.
47. J Sports Med Phys Fitness. 2000 Sep;40(3):240-6.
48. Sports Med. 1999 Jun;27(6):347-58.
49. Proc Natl Acad Sci USA. 2010 Jan 5;107(1):366-71.
Supplement Facts
Serving Size 4 capsules
Servings Per Container approximately 22
Amount Per Serving
L-Leucine 1200 mg
L-Isoleucine 600 mg
L-Valine 600 mg
Other ingredients: vegetable cellulose (capsule), rice flour.
Contains rice.
This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, corn. Contains NO artificial sweeteners, flavors, colors, or preservatives.
Dosage and Use
To be used by adults 18 years and older.
Take four capsules daily with or without food, or as recommended by a healthcare practitioner.
Caution
Individuals with ALS or disorders impairing the metabolism of branched amino acids should not use this product.
Keep out of reach of children.
Do not exceed recommended dose.
Do not purchase if outer seal is broken or damaged.
If you have a bad reaction to product discontinue use immediately.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
References
34. Med Sci Sports Exerc. 1998 Jan;30(1):83-91.
35. J Nutr. 2001 Apr;131(4):1171-6.
36. Surgery. 1981 Aug;90(2):237-43.
37. Clin Gastroenterol Hepatol. 2005 Jul;3(7):705-13.
38. Aliment Pharmacol Ther. 2004 Apr 1;19(7):779-88.
39. Hepatogastoenterology. 2009 Sep-Oct;56(94-95):1491-5.
40. Intern Med. 1998 May;37(5):429-34
41. Int J Mol Med. 2008 Jul;22(1):105-12.
42. Liver Int. 2007 Nov;27(9): 1287-92
43. Nutrition. 1996 Jul-Aug;12(7-8):485-90.
44. J Physiol. 1996 Jun 15;493 ( Pt 3):909-22.
45. Eur J Appl Physiol Occup Physiol. 1994;69(1):26-31.
46. Acta Physiol Scand. 1992 Nov;146(3):293-8.
47. J Sports Med Phys Fitness. 2000 Sep;40(3):240-6.
48. Sports Med. 1999 Jun;27(6):347-58.
49. Proc Natl Acad Sci USA. 2010 Jan 5;107(1):366-71.
Supplement Facts
Serving Size 4 capsules
Servings Per Container approximately 22
Amount Per Serving
L-Leucine 1200 mg
L-Isoleucine 600 mg
L-Valine 600 mg
Other ingredients: vegetable cellulose (capsule), rice flour.
Contains rice.
This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, corn. Contains NO artificial sweeteners, flavors, colors, or preservatives.
Dosage and Use
To be used by adults 18 years and older.
Take four capsules daily with or without food, or as recommended by a healthcare practitioner.
Caution
Individuals with ALS or disorders impairing the metabolism of branched amino acids should not use this product.
Keep out of reach of children.
Do not exceed recommended dose.
Do not purchase if outer seal is broken or damaged.
If you have a bad reaction to product discontinue use immediately.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
