Gamma E Tocopherol with Sesame Lignans
According to the Proceedings of the National Academy of Sciences, alpha tocopherol (regular vitamin E) displaces critically important gamma tocopherol in the cells (121). While alpha tocopherol inhibits free radical production, gamma tocopherol is required to trap and neutralize existing free radicals (121).
Prestigious scientific journals have highlighted gamma tocopherol as one of the most critically important forms of vitamin E for those seeking optimal health benefits. In fact, studies shows the combination of alpha- and gamma-tocopherol supplementation appears to be superior to either supplementation alone on biomarkers of oxidative stress and on inflammatory factors (122,123).
Most commercial vitamin E supplements contain little, if any, gamma tocopherol. They instead rely on alpha tocopherol as the primary ingredient. However, it is gamma tocopherol (not the alpha form) that quenches peroxynitrite, the free radical that plays a major role in the development of age-related decline (121).
Sesame Lignans: The Natural Vitamin E Booster
Life Extension® has uncovered research suggesting that adding sesame lignans to gamma tocopherol may significantly enhance its beneficial effects (124,125). Sesame and its lignans have been shown to boost antioxidative activity in the tissues by elevating the levels of two antioxidative vitamins, vitamin C and E (126).
In a human study that combined gamma tocopherol with sesame lignans, gamma tocopherol/sesame was 25% more effective than gamma tocopherol/tocotrienols in suppressing tissue measurements for free radical and inflammatory damage (126a). Since tocotrienols are considered nature's most potent antioxidants, the fact that low-cost gamma tocopherol with sesame is more effective is a remarkable finding.
Life Extension has fortified the popular Gamma E Tocopherol supplement with standardized sesame lignans. Consumers obtain superior benefits at a much lower cost. This formula provides potent doses of gamma tocopherol along with sesame lignan extract to augment the antioxidant effects of gamma tocopherol.
References
121. Proc Natl Acad Sci USA. 1997 Apr 1; 94(7):3217-22.
122. Free Radic Biol Med. 2008 Mar 15;44(6):1203-8.
123. Eur J Nutr. 2008 Oct;47(7):387-92.
124. J Nutr. 1992 Dec;122(12):2440-6.
125. Lipids. 1995 Nov;30(11):1019-28.
126. J Nutr Sci Vitaminol (Tokyo). 2007 Oct;53(5):383-92.
126a. Life Extension internal study.
Supplement Facts
Serving Size 1 softgel
Servings Per Container 60
Amount Per Serving
Vitamin E (as D-alpha tocopherol) 45 IU
Gamma E Mixed Tocopherols 359 mg
Typical profile:
Gamma tocopherol 215,4-244,12 mg
Delta tocopherol 89,75-125,65 mg
Alpha tocopherol 30,51-35,9 mg
Beta tocopherol 0-7,18 mg
Sesame seed (Sesamum indicum) lignan extract 20 mg
Other ingredients: gelatin, glycerin, water, carob, lecithin, silica, rosemary.
Contains soybeans. Contains sesame.
This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), tree nuts, wheat, yeast, gluten, corn or rice. Contains NO sugar, artificial sweeteners, flavors, colors, or preservatives.
Dosage and Use
Take one softgel once or twice daily with food, or as recommended by a healthcare practitioner.
Caution
If you are taking anti-coagulant or anti-platelet medications, or have a bleeding disorder, consult your healthcare provider before taking this product.
Keep out of reach of children.
Do not exceed recommended dose.
Do not purchase if outer seal is broken or damaged.
If you have a bad reaction to product discontinue use immediately.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Prestigious scientific journals have highlighted gamma tocopherol as one of the most critically important forms of vitamin E for those seeking optimal health benefits. In fact, studies shows the combination of alpha- and gamma-tocopherol supplementation appears to be superior to either supplementation alone on biomarkers of oxidative stress and on inflammatory factors (122,123).
Most commercial vitamin E supplements contain little, if any, gamma tocopherol. They instead rely on alpha tocopherol as the primary ingredient. However, it is gamma tocopherol (not the alpha form) that quenches peroxynitrite, the free radical that plays a major role in the development of age-related decline (121).
Sesame Lignans: The Natural Vitamin E Booster
Life Extension® has uncovered research suggesting that adding sesame lignans to gamma tocopherol may significantly enhance its beneficial effects (124,125). Sesame and its lignans have been shown to boost antioxidative activity in the tissues by elevating the levels of two antioxidative vitamins, vitamin C and E (126).
In a human study that combined gamma tocopherol with sesame lignans, gamma tocopherol/sesame was 25% more effective than gamma tocopherol/tocotrienols in suppressing tissue measurements for free radical and inflammatory damage (126a). Since tocotrienols are considered nature's most potent antioxidants, the fact that low-cost gamma tocopherol with sesame is more effective is a remarkable finding.
Life Extension has fortified the popular Gamma E Tocopherol supplement with standardized sesame lignans. Consumers obtain superior benefits at a much lower cost. This formula provides potent doses of gamma tocopherol along with sesame lignan extract to augment the antioxidant effects of gamma tocopherol.
References
121. Proc Natl Acad Sci USA. 1997 Apr 1; 94(7):3217-22.
122. Free Radic Biol Med. 2008 Mar 15;44(6):1203-8.
123. Eur J Nutr. 2008 Oct;47(7):387-92.
124. J Nutr. 1992 Dec;122(12):2440-6.
125. Lipids. 1995 Nov;30(11):1019-28.
126. J Nutr Sci Vitaminol (Tokyo). 2007 Oct;53(5):383-92.
126a. Life Extension internal study.
Supplement Facts
Serving Size 1 softgel
Servings Per Container 60
Amount Per Serving
Vitamin E (as D-alpha tocopherol) 45 IU
Gamma E Mixed Tocopherols 359 mg
Typical profile:
Gamma tocopherol 215,4-244,12 mg
Delta tocopherol 89,75-125,65 mg
Alpha tocopherol 30,51-35,9 mg
Beta tocopherol 0-7,18 mg
Sesame seed (Sesamum indicum) lignan extract 20 mg
Other ingredients: gelatin, glycerin, water, carob, lecithin, silica, rosemary.
Contains soybeans. Contains sesame.
This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), tree nuts, wheat, yeast, gluten, corn or rice. Contains NO sugar, artificial sweeteners, flavors, colors, or preservatives.
Dosage and Use
Take one softgel once or twice daily with food, or as recommended by a healthcare practitioner.
Caution
If you are taking anti-coagulant or anti-platelet medications, or have a bleeding disorder, consult your healthcare provider before taking this product.
Keep out of reach of children.
Do not exceed recommended dose.
Do not purchase if outer seal is broken or damaged.
If you have a bad reaction to product discontinue use immediately.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
