Gentle-C
Vitamin C, or ascorbic acid, is a white, crystalline, water-soluble substance found in citrus fruits and green vegetables. As an antioxidant, vitamin C scavenges free radicals in the body and protects tissues from oxidative stress (15-18,21-24). Vitamin C also promotes the absorption of iron, while preventing its oxidation (19,20,25-27). Vitamin C is a vital co-factor to the formation of collagen, the connective tissue that supports arterial walls, skin, bones, and teeth (22-27).
More vitamin C is contained in the adrenal glands than any other organ in the body and is required at higher levels during times of stress (28,31). Physical stresses on the body such as ingestion of heavy metals (32-37), cigarette smoking (38-41), infections (45), extreme temperatures (46-50), and chronic use of certain medications such as aspirin also signal the need for increased intake of vitamin C (51).
This TwinLab® product contains a unique calcium-bound ascorbate complex. This is a non-acidic form of vitamin C that may have a longer serum half-life than regular ascorbic acid (62-66). The product also contains a citrus bioflavonoid complex.
References
15. Indian J Exp Biol. 1997 Mar;35(3):264-6.
16. Am J Clin Nutr. 1996 Jun;63(6):985S-990S.
17. FASEB J. 1995 Apr;9(7):526-33.
18. J Am Coll Nutr. 1995 Apr;14(2):124-36.
19. Clin Physiol Biochem. 1986;4(1):78-86.
20. Int J Vitam Nutr Res. 1980;50(3):301-8.
21. Altern Med Rev. 2003 Nov;8(4):359-77.
22. J Invest Dermatol. 2002 Apr;118(4):565-72.
23. Yale J Biol Med. 1985 Nov-Dec;58(6):553-9.
24. Free Radic Biol Med. 2007 Sep 1;43(5):853-9.
25. Psychopharmacology (Berl). 2002 Jan;159(3):319-24.
26. In Vivo. 1994 Nov-Dec;8(6):1079-85.
27. Anesteziol Reanimatol. 1990 Sep-Oct;(5):71-4.
28. Res Vet Sci. 1981 Sep;31(2):219-23.
31. Respir Med. 2007 Aug;101(8):1770-8.
32. Mutat Res. 1990 Jul;241(3):305-12.
33. Environ Mol Mutagen. 1993;21(3):229-36.
34. Exp Lung Res. 1998 Mar-Apr;24(2):219-32.
35. J Nutr. 1994 Jun;124(6 Suppl):981S-986S.
36. Biomed Environ Sci. 1998 Mar;11(1):7-14.
37. Toxicology. 2002 Nov 15;180(2):121-37.
38. Environ Health Perspect. 2000 Feb;108(2):105-8.
39. Indian J Public Health. 1998 Jan-Mar;42(1):20-3.
40. Prog Food Nutr Sci. 1991;15(4):183-217.
41. J Am Coll Cardiol. 2003 Nov 5;42(9):1656-62.
45. Br J Dermatol. 1980 Jan;102(1):49-56.
46. Indian J Med Res. 2002 Jul;116:29-34.
47. Indian J Med Res. 1993 Aug;98:178-84.
48. Vopr Pitan. 1978 Jan-Feb;(1):44-8.
49. J Nutr. 1989 Mar;119(3):425-7.
50. Tohoku J Exp Med. 1967 Jun;92(2):207-19.
51. Med Sci Monit. 2001 Jul-Aug;7(4):592-9.
62. J Physiol Pharmacol. 2005 Sep;56 Suppl 4:197-201.
63. J Biomed Sci. 2003 Mar-Apr;10(2):193-8.
64. Anticancer Drugs. 1993 Feb;4(1):91-6.
65. Am J Clin Nutr. 1988 Sep;48(3):601-4.
66. Res Commun Chem Pathol Pharmacol. 1987 Jul;57(1):137-40
Supplement Facts
Serving Size 1 tablet
Servings Per Container 100
Amount Per Serving
Vitamin C (as calcium ascorbate) 1000 mg
Calcium (as calcium ascorbate) 100 mg
Citrus bioflavonoid complex 200 mg
Other ingredients: cellulose, croscarmelose sodium, vegetable stearic acid, silica, magnesium stearate, glycerin.
Free of salt (sodium), wheat, starch, yeast, dairy, artificial colors, flavors and preservatives.
Dosage and Use
One or more tablets daily.
Warnings:
Keep out of reach of children.
Do not exceed recommended dose.
Do not purchase if outer seal is broken or damaged.
If you have a bad reaction to product discontinue use immediately.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
More vitamin C is contained in the adrenal glands than any other organ in the body and is required at higher levels during times of stress (28,31). Physical stresses on the body such as ingestion of heavy metals (32-37), cigarette smoking (38-41), infections (45), extreme temperatures (46-50), and chronic use of certain medications such as aspirin also signal the need for increased intake of vitamin C (51).
This TwinLab® product contains a unique calcium-bound ascorbate complex. This is a non-acidic form of vitamin C that may have a longer serum half-life than regular ascorbic acid (62-66). The product also contains a citrus bioflavonoid complex.
References
15. Indian J Exp Biol. 1997 Mar;35(3):264-6.
16. Am J Clin Nutr. 1996 Jun;63(6):985S-990S.
17. FASEB J. 1995 Apr;9(7):526-33.
18. J Am Coll Nutr. 1995 Apr;14(2):124-36.
19. Clin Physiol Biochem. 1986;4(1):78-86.
20. Int J Vitam Nutr Res. 1980;50(3):301-8.
21. Altern Med Rev. 2003 Nov;8(4):359-77.
22. J Invest Dermatol. 2002 Apr;118(4):565-72.
23. Yale J Biol Med. 1985 Nov-Dec;58(6):553-9.
24. Free Radic Biol Med. 2007 Sep 1;43(5):853-9.
25. Psychopharmacology (Berl). 2002 Jan;159(3):319-24.
26. In Vivo. 1994 Nov-Dec;8(6):1079-85.
27. Anesteziol Reanimatol. 1990 Sep-Oct;(5):71-4.
28. Res Vet Sci. 1981 Sep;31(2):219-23.
31. Respir Med. 2007 Aug;101(8):1770-8.
32. Mutat Res. 1990 Jul;241(3):305-12.
33. Environ Mol Mutagen. 1993;21(3):229-36.
34. Exp Lung Res. 1998 Mar-Apr;24(2):219-32.
35. J Nutr. 1994 Jun;124(6 Suppl):981S-986S.
36. Biomed Environ Sci. 1998 Mar;11(1):7-14.
37. Toxicology. 2002 Nov 15;180(2):121-37.
38. Environ Health Perspect. 2000 Feb;108(2):105-8.
39. Indian J Public Health. 1998 Jan-Mar;42(1):20-3.
40. Prog Food Nutr Sci. 1991;15(4):183-217.
41. J Am Coll Cardiol. 2003 Nov 5;42(9):1656-62.
45. Br J Dermatol. 1980 Jan;102(1):49-56.
46. Indian J Med Res. 2002 Jul;116:29-34.
47. Indian J Med Res. 1993 Aug;98:178-84.
48. Vopr Pitan. 1978 Jan-Feb;(1):44-8.
49. J Nutr. 1989 Mar;119(3):425-7.
50. Tohoku J Exp Med. 1967 Jun;92(2):207-19.
51. Med Sci Monit. 2001 Jul-Aug;7(4):592-9.
62. J Physiol Pharmacol. 2005 Sep;56 Suppl 4:197-201.
63. J Biomed Sci. 2003 Mar-Apr;10(2):193-8.
64. Anticancer Drugs. 1993 Feb;4(1):91-6.
65. Am J Clin Nutr. 1988 Sep;48(3):601-4.
66. Res Commun Chem Pathol Pharmacol. 1987 Jul;57(1):137-40
Supplement Facts
Serving Size 1 tablet
Servings Per Container 100
Amount Per Serving
Vitamin C (as calcium ascorbate) 1000 mg
Calcium (as calcium ascorbate) 100 mg
Citrus bioflavonoid complex 200 mg
Other ingredients: cellulose, croscarmelose sodium, vegetable stearic acid, silica, magnesium stearate, glycerin.
Free of salt (sodium), wheat, starch, yeast, dairy, artificial colors, flavors and preservatives.
Dosage and Use
One or more tablets daily.
Warnings:
Keep out of reach of children.
Do not exceed recommended dose.
Do not purchase if outer seal is broken or damaged.
If you have a bad reaction to product discontinue use immediately.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

















