B12
Vitamin B12 is present in foods of animal origin, including dairy products and eggs. Thus, vegetarians are more susceptible to a dietary deficiency of this important nutrient (212). Likewise, vitamin B12 serum concentrations are reported to be significantly lower in elderly population groups compared to younger groups (213-216). It is estimated that 10% to 30% of individuals over the age of 50 have low stomach acid secretion (217,218) which results in decreased bioavailability of vitamin B12 from food. To overcome food-bound vitamin B12 malabsorption problems, the Institute of Medicine recommends that vitamin B12-fortified foods (such as fortified ready-to-eat breakfast cereals) or supplements containing vitamin B12 be used to meet much of the requirement (219). Vitamin B12, or cobalamin, works synergistically with vitamin B6 and folate to regenerate (methylate) the amino acid methionine, which helps to maintain already healthy homocysteine levels already within normal range, which is important for heart health (220,221).
Cyanocobalamin is a synthetic and inexpensive form of vitamin B12 that is converted in the body to its bioactive forms, methylcobalamin and cobamamide.
References
212. Exp Biol Med (Maywood). 2007 Nov;232(10):1266-74.
213. Am J Clin Nutr. 1999;70:904-910.
214. Am J Clin Nutr. 1994;60:2-11.
215. Am J Clin Nutr. 1994;60:12-14.
216. Prev Med. 2004 Dec;39(6):1256-66.
217. JAMA. 1997 Aug 27;278(8):659-62.
218. J Am Geriatr Soc. 1986 Nov;34(11):800-6.
219. Nutr Rev. 2004 Jun;62(6 Pt 2):S3-S12.
220. Lancet. 2002 Jan 19;359(9302):227-8.
221. Asia Pac J Clin Nutr. 2007;16(1):103-9.
Supplement Facts
Serving Size 1 lozenge
Servings Per Container 100
Amount Per Serving
Vitamin B12 (as cyanocobalamin) 500 mcg
Other ingredients: mannitol, sorbitol, microcrystalline cellulose, vegetable stearate, croscarmellose sodium, natural strawberry flavor.
Contains corn.
This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, or rice. Contains NO artificial sweeteners, flavors, colors, or preservatives.
Dosage and Use
Take one lozenge one to four times daily with or without food, or as recommended by a healthcare practitioner.
Place lozenge in mouth and allow to dissolve, then swallow.
Caution:
Keep out of reach of children.
Do not exceed recommended dose.
Do not purchase if outer seal is broken or damaged.
If you have a bad reaction to product discontinue use immediately.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Cyanocobalamin is a synthetic and inexpensive form of vitamin B12 that is converted in the body to its bioactive forms, methylcobalamin and cobamamide.
References
212. Exp Biol Med (Maywood). 2007 Nov;232(10):1266-74.
213. Am J Clin Nutr. 1999;70:904-910.
214. Am J Clin Nutr. 1994;60:2-11.
215. Am J Clin Nutr. 1994;60:12-14.
216. Prev Med. 2004 Dec;39(6):1256-66.
217. JAMA. 1997 Aug 27;278(8):659-62.
218. J Am Geriatr Soc. 1986 Nov;34(11):800-6.
219. Nutr Rev. 2004 Jun;62(6 Pt 2):S3-S12.
220. Lancet. 2002 Jan 19;359(9302):227-8.
221. Asia Pac J Clin Nutr. 2007;16(1):103-9.
Supplement Facts
Serving Size 1 lozenge
Servings Per Container 100
Amount Per Serving
Vitamin B12 (as cyanocobalamin) 500 mcg
Other ingredients: mannitol, sorbitol, microcrystalline cellulose, vegetable stearate, croscarmellose sodium, natural strawberry flavor.
Contains corn.
This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, or rice. Contains NO artificial sweeteners, flavors, colors, or preservatives.
Dosage and Use
Take one lozenge one to four times daily with or without food, or as recommended by a healthcare practitioner.
Place lozenge in mouth and allow to dissolve, then swallow.
Caution:
Keep out of reach of children.
Do not exceed recommended dose.
Do not purchase if outer seal is broken or damaged.
If you have a bad reaction to product discontinue use immediately.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
