Vitamin B3 Niacin
Niacin is the only B vitamin that can be synthesized in the body from the amino acid tryptophan (180-183). In its coenzyme forms, niacin is crucial to energy transfer reactions, particularly the metabolism of glucose, fat, and alcohol (184,185). Niacin's beneficial effects on blood lipids is well documented (186-201).
References
180. J Am Diet Assoc. 1989 Dec;89(12):1748-52.
181. Nutr Rev. 1975 Oct;33(10):289-97.
181a. Biofactors.2006;26(3):201-8.
182. J Am Geriatr Soc. 1992 Jan;40(1):12-8.
183. Eur J Clin Pharmacol. 1991;40 Suppl 1:S49-S51.
184. JAMA. 1990 Dec 19;264(23):3013-7.
185. Metabolism. 1985 Jul;34(7):642-50.
186. Arch Intern Med. 2002 Jul 22;162(14):1568-76.
187. Arterioscler Thromb Vasc Biol. 2001 Nov;21(11):1783-9.
188. JAMA. 2000 Sep 13;284(10):1263-70.
189. Arch Intern Med. 2000 Apr 24;160(8):1177-84.
190. Am J Cardiol. 2000 May 1;85(9):1100-5.
191. Circulation. 1993 Jul;88(1):20-8.
192. Am J Cardiol. 1998 Sep 15;82(6):737-43.
193. JAMA. 1994 Mar 2;271(9):672-7.
194. Am J Med. 1994 Oct;97(4):323-31.
195. Arch Intern Med. 1994 Jul 25;154(14):1586-95.
196. Pediatr Res. 1992 Apr;31(4 Pt 1):419-23.
197. Vitam Horm. 1991;46:165-228. Review.
198. Br J Pharmacol. 1988 Sep;95(1):77-82.
199. Farmakol Toksikol. 1988 Sep-Oct;51(5):82-6.
200. Acta Vitaminol Enzymol. 1982;4(1-2):105-14.
201. Am J Clin Dermatol. 2002;3(6):427-33.
Supplement Facts
Serving Size 1 capsule
Servings Per Container 100
Amount Per Serving
Niacin (vitamin B3) 1000 mg
Other ingredients: gelatin, magnesium stearate
This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, corn, or rice. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives.
Dosage and Use
Take one capsule daily with meals, or as recommended by a healthcare practitioner.
Note
Niacinamide is another B3 vitamin that does not cause flushing.
Caution
Temporary flushing, itching, rash, or gastric disturbances may occur. Periodic liver function testing and supervision of a qualified healthcare professional are strongly recommended with niacin dosing in excess of 500 mg daily. Those with gout or liver diseases should avoid taking high doses of niacin.
Keep out of reach of children.
Do not exceed recommended dose.
Do not purchase if outer seal is broken or damaged.
If you have a bad reaction to product discontinue use immediately.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
References
180. J Am Diet Assoc. 1989 Dec;89(12):1748-52.
181. Nutr Rev. 1975 Oct;33(10):289-97.
181a. Biofactors.2006;26(3):201-8.
182. J Am Geriatr Soc. 1992 Jan;40(1):12-8.
183. Eur J Clin Pharmacol. 1991;40 Suppl 1:S49-S51.
184. JAMA. 1990 Dec 19;264(23):3013-7.
185. Metabolism. 1985 Jul;34(7):642-50.
186. Arch Intern Med. 2002 Jul 22;162(14):1568-76.
187. Arterioscler Thromb Vasc Biol. 2001 Nov;21(11):1783-9.
188. JAMA. 2000 Sep 13;284(10):1263-70.
189. Arch Intern Med. 2000 Apr 24;160(8):1177-84.
190. Am J Cardiol. 2000 May 1;85(9):1100-5.
191. Circulation. 1993 Jul;88(1):20-8.
192. Am J Cardiol. 1998 Sep 15;82(6):737-43.
193. JAMA. 1994 Mar 2;271(9):672-7.
194. Am J Med. 1994 Oct;97(4):323-31.
195. Arch Intern Med. 1994 Jul 25;154(14):1586-95.
196. Pediatr Res. 1992 Apr;31(4 Pt 1):419-23.
197. Vitam Horm. 1991;46:165-228. Review.
198. Br J Pharmacol. 1988 Sep;95(1):77-82.
199. Farmakol Toksikol. 1988 Sep-Oct;51(5):82-6.
200. Acta Vitaminol Enzymol. 1982;4(1-2):105-14.
201. Am J Clin Dermatol. 2002;3(6):427-33.
Supplement Facts
Serving Size 1 capsule
Servings Per Container 100
Amount Per Serving
Niacin (vitamin B3) 1000 mg
Other ingredients: gelatin, magnesium stearate
This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, corn, or rice. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives.
Dosage and Use
Take one capsule daily with meals, or as recommended by a healthcare practitioner.
Note
Niacinamide is another B3 vitamin that does not cause flushing.
Caution
Temporary flushing, itching, rash, or gastric disturbances may occur. Periodic liver function testing and supervision of a qualified healthcare professional are strongly recommended with niacin dosing in excess of 500 mg daily. Those with gout or liver diseases should avoid taking high doses of niacin.
Keep out of reach of children.
Do not exceed recommended dose.
Do not purchase if outer seal is broken or damaged.
If you have a bad reaction to product discontinue use immediately.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
