Mega GLA with Sesame Lignans
Omega-6 fatty acids are well-supplied in the diet by meat and vegetable oils. However, not all omega-6 fatty acids are of equal value. Linoleic acid (not to be confused with ALA, which is in the omega-3 family) and arachidonic acid (AA) tend to be unhealthy because they are the precursor of inflammatory eicosanoids, such as prostaglandin E2 (PGE2), thromboxane A2, and leukotriene B4, which promote inflammation. In contrast, gamma linolenic acid (GLA), found in evening primrose oil, borage oil, and black currant oil, is an important fatty acid that plays a beneficial role in healthy prostaglandin formation (59). Health conscious people have been consuming a lot of borage oil to obtain GLA, the parent of the biologically active DGLA (di-homo-gamma-linolenic acid).
Life Extension's Mega GLA provides 285 mg of GLA plus 10 milligrams of sesame lignans. These sesame lignans increase beneficial DGLA, and they also help reduce the production of proinflammatory arachidonic acid, which is responsible for the formation of destructive prostaglandin E2 and leukotriene B4 (60). Numerous studies have documented GLAs multiple health effects, but information about the ability of sesame to prevent the conversion of GLA into arachidonic acid indicates that many more people may now be able to benefit from supplementing with GLA (61).
References
59. Arthritis Rheum. 1996 Nov;39(11):1808-17
60. Prostaglandins Leukot Essent Fatty Acids. 1998 Mar,58(3):185-91.
61. J Nutri Sci Vitaminol. 2003 Dec;49(6):442-6.
Supplement Facts
Serving Size 1 softgel
Servings Per Container 60
Amount Per Serving
Calories 15
Calories from fat 15
Total Fat 1.3 g
Saturated fat 0.0 g
Borage seed oil (Borago officinalis) supplying 299 mg gamma-linolenic acid (GLA) 1300 mg
Sesame seed (Sesamum indicum) lignan extract 10 mg
Other ingredients: gelatin, glycerin, purified water, silica, soy lecithin, rosemary, carob.
Contains soybeans. Contains sesame.
This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster crab, shrimp), tree nuts, wheat, yeast, gluten, corn, or rice. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives.
Dosage and Use
Take one softgel one to two times daily with food, or as recommended by a healthcare practitioner.
Up to five softgels can be taken daily.
Caution
If you are taking anti-coagulant or anti-platelet medications, or have a bleeding disorder, consult your healthcare provider before taking this product.
Caution:
Keep out of reach of children.
Do not exceed recommended dose.
Do not purchase if outer seal is broken or damaged.
If you have a bad reaction to product discontinue use immediately.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Life Extension's Mega GLA provides 285 mg of GLA plus 10 milligrams of sesame lignans. These sesame lignans increase beneficial DGLA, and they also help reduce the production of proinflammatory arachidonic acid, which is responsible for the formation of destructive prostaglandin E2 and leukotriene B4 (60). Numerous studies have documented GLAs multiple health effects, but information about the ability of sesame to prevent the conversion of GLA into arachidonic acid indicates that many more people may now be able to benefit from supplementing with GLA (61).
References
59. Arthritis Rheum. 1996 Nov;39(11):1808-17
60. Prostaglandins Leukot Essent Fatty Acids. 1998 Mar,58(3):185-91.
61. J Nutri Sci Vitaminol. 2003 Dec;49(6):442-6.
Supplement Facts
Serving Size 1 softgel
Servings Per Container 60
Amount Per Serving
Calories 15
Calories from fat 15
Total Fat 1.3 g
Saturated fat 0.0 g
Borage seed oil (Borago officinalis) supplying 299 mg gamma-linolenic acid (GLA) 1300 mg
Sesame seed (Sesamum indicum) lignan extract 10 mg
Other ingredients: gelatin, glycerin, purified water, silica, soy lecithin, rosemary, carob.
Contains soybeans. Contains sesame.
This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster crab, shrimp), tree nuts, wheat, yeast, gluten, corn, or rice. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives.
Dosage and Use
Take one softgel one to two times daily with food, or as recommended by a healthcare practitioner.
Up to five softgels can be taken daily.
Caution
If you are taking anti-coagulant or anti-platelet medications, or have a bleeding disorder, consult your healthcare provider before taking this product.
Caution:
Keep out of reach of children.
Do not exceed recommended dose.
Do not purchase if outer seal is broken or damaged.
If you have a bad reaction to product discontinue use immediately.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
