Mineral Formula for Women
Calcium is the most popular mineral supplement on the market, yet certain forms of calcium tablets are often poorly absorbed by the digestive systems of older people because of insufficient stomach acid (6). The Life Extension Foundation Buyers Club supplies calcium and almost all other mineral supplements only in the form of finely divided mineral powders within capsules that easily disintegrate in the stomach for optimal absorption. Studies have also shown that certain mineral compounds are absorbed better than others (7-10).
Calcium is the most abundant mineral in the body where it is primarily found in bones and teeth. In bone formation, calcium forms crystals that provide strength to maturing bone. Peak bone mass is usually achieved when people are in their 20's.
Calcium is needed for more than just healthy bones. It is also important for muscle contraction, blood vessel contraction and expansion, the secretion of hormones and enzymes, and sending messages through the nervous system. A meta-analysis of 56 clinical trials demonstrated a significant impact on heart health resulting from increasing calcium intake by 1000 to 2000 mg/day (11). In addition, recent evidence suggests that increased intake of calcium may help in weight control as well (12-15).
Magnesium is one of the body's most important minerals. It is required as a co-factor in hundreds of enzymatic processes within cells (16). It helps maintain normal muscle and nerve function, keeps heart rhythm steady, supports a healthy immune system, and keeps bones strong. Magnesium also helps to maintain blood sugar and blood pressure levels already within normal range, and is known to be involved in energy metabolism and protein synthesis (17,18).
Magnesium is a major factor in relaxing the smooth muscles within the blood vessels, thereby reducing peripheral vascular resistance and promoting a healthy cardiovascular system (19-21). Magnesium also affects circulating levels of norepinephrine and the synthesis of serotonin and nitric oxide (16,22-24).
In bone mineral health, magnesium (or lack of) influences the bone mineral matrix and its ability to metabolize minerals needed for repair and rebuilding (25, 26). The scientific literature documents the need for a wide range of minerals that are vital to maintaining strong, healthy bones.
Calcium and other minerals are best not taken with fiber, because fiber can interfere with their absorption (1-5). There is evidence that calcium from supplements and dairy foods may inhibit iron absorption, although it has been very difficult to distinguish between the effects of calcium on iron absorption versus other inhibitory factors such as phytate (27).
Therefore, if you are iron deficient, it may be best to avoid taking calcium with meals (28). Calcium supplements are best administered at dinner and/or bedtime. They should always be taken with a full glass of water, juice, or other liquid to enhance solubility (29). If calcium-containing formulas are taken only once daily they may be best taken in the evening (30)
A problem overlooked by most doctors is that loss of bone density is associated with deficiencies of not just calcium, but a host of other nutrients including magnesium and vitamin D3 (31-37). In order for calcium to prevent bone loss, adequate amounts of vitamin D3, zinc, manganese and other nutrients should be available so that calcium, magnesium, and phosphorus can be incorporated into the bone matrix (38-46). Another issue that many people are not aware of is that many forms of calcium do not absorb particularly well (47,48).
Mineral Formula for Women reflects the need of women for more calcium than men. This product should be taken as an addition to Life Extension Mix™. Vitamin D is included to aid in calcium absorption and utilization.
References
1. J Nutr. 1992 Mar;122(3):442-9.
2. Proc Soc Exp Biol Med. 1985 Dec;180(3):432-46.
3. Am J Clin Nutr. 1983 Jul;38(1):12-9.
4. Am J Clin Nutr. 1979 Sep;32(9):1876-80.
5. Lancet. 1973 Feb 10;1(7798):283-8.
6. N Engl J Med. 1985 Jul 11;313(2):70-3.
7. Am J Ther. 1999 Nov;6(6):313-21.
8. J Am Coll Nutr. 1990 Dec;9(6):583-7.
9. J Bone Miner Res. 1988 Jun;3(3):253-8.
10. J Clin Endocrinol Metab. 1985 Aug;61(2):391-3.
11. JAMA. 1996 Apr 3;275(13):1016-22.
12. FASEB J. 2000 Jun;14(9):1132-8.
13. J Am Coll Nutr. 2000 Nov-Dec;19(6):754-60.
14. Int J Obes Relat Metab Disord. 2001 Apr;25(4):559-66.
15. FASEB J. 2001 Feb;15(2):291-3.
16. J Bone Miner Res. 1998 Apr;13(4):749-58.
17. Am J Clin Nutr 1987;45:1305-12.
18. Clinica Chimica Acta 2000;294:1-26.
19. Ann Pharmacother. 2002 Feb;36(2):255-60.
20. Br J Sports Med. 2006 Sep;40(9):773-8.
21. Congest Heart Fail. 2006 Jan-Feb;12(1):9-13
22. Am Heart J. 1984 Jul;108(1):188-93.
23. Angiology. 1994 Jul;45(7):637-45.
24. Magnes Res. 2006 Jun;19(2):113-22.
25. Nutr Rev. 1995 Sep;53(9 Pt 2):S23-S27.
26. J Clin Endocrinol Metab. 1998 Aug;83(8):2742-8.
27. Institute of Medicine Washington, DC: National Academy Press, 2001.
28. Am J Clin Nutr. 1991 Jan;53(1):106-11.
29. Public Health Rep. 1989 Sep-Oct;104 Suppl:46-50.
30. J Clin Endocrinol Metab. 1994 Sep;79(3):730-5.
31. Magnes Trace Elem. 1990;9(2):61-9.
32. Curr Pharm Des. 2003;9(32):2687-704.
33. Biol Trace Elem Res. 28:243-55, 1991.
34. Magnes Res. 1993 Jun;6(2):155-63.
35. J Reprod Med. 1990 May;35(5):503-7.
36. Gynecol Endocrinol. 1994 Mar;8(1):55-8.
37. J Clin Endocrinol Metab. 2006 Dec;91(12):4866-72
38. Eur J Obstet Gynecol Reprod Biol. 2000 May;90(1):97-101.
39. Arch Tierernahr. 1992;42(1):25-35.
40. Sci News. 1986; Sept. 27:199
41. J Am Coll Nutr. 1993;12:384-389
42. Orhtopedics. 1974;103:212-234
43. Acta Orthop Scand. 1977 May;48(1):1-4.
44. Acta Med Scand. 1980;207(1-2):67-70.
45. J Nutr. 1994 Jul;124(7):1060-4.
46. Crit Care Nurs Q. 2004 Jan-Mar;27(1):96-100.
47. Altern Med Rev. 1999 Apr;4(2):74-85.
48. Calcif Tissue Int. 1990 May;46(5):300-4.
Supplement Facts
Serving Size 1 capsule
Servings Per Container 100
Amount Per Serving
Vitamin D (as cholecalciferol) 100 IU
Calcium (as calcium citrate, malate, and succinate) 123 mg
Magnesium 100 mg
Manganese (as manganese gluconate) 0.25 mg
Potassium (as potassium aspartate) 8.05 mg
Other ingredients: gelatin, vegetable stearate, rice flour.
Contains corn and rice.
This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, or gluten. Contains NO artificial sweeteners, flavors, colors, or preservatives.
Dosage and Use
Take one capsule one to four times daily with or without food, or as recommended by a healthcare practitioner.
Total intake of calcium greater than 2000 mg per day provides no added benefit to bone health.
Warnings
Keep out of reach of children.
Do not exceed recommended dose.
Do not purchase if outer seal is broken or damaged.
If you have a bad reaction to product discontinue use immediately.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Calcium is the most abundant mineral in the body where it is primarily found in bones and teeth. In bone formation, calcium forms crystals that provide strength to maturing bone. Peak bone mass is usually achieved when people are in their 20's.
Calcium is needed for more than just healthy bones. It is also important for muscle contraction, blood vessel contraction and expansion, the secretion of hormones and enzymes, and sending messages through the nervous system. A meta-analysis of 56 clinical trials demonstrated a significant impact on heart health resulting from increasing calcium intake by 1000 to 2000 mg/day (11). In addition, recent evidence suggests that increased intake of calcium may help in weight control as well (12-15).
Magnesium is one of the body's most important minerals. It is required as a co-factor in hundreds of enzymatic processes within cells (16). It helps maintain normal muscle and nerve function, keeps heart rhythm steady, supports a healthy immune system, and keeps bones strong. Magnesium also helps to maintain blood sugar and blood pressure levels already within normal range, and is known to be involved in energy metabolism and protein synthesis (17,18).
Magnesium is a major factor in relaxing the smooth muscles within the blood vessels, thereby reducing peripheral vascular resistance and promoting a healthy cardiovascular system (19-21). Magnesium also affects circulating levels of norepinephrine and the synthesis of serotonin and nitric oxide (16,22-24).
In bone mineral health, magnesium (or lack of) influences the bone mineral matrix and its ability to metabolize minerals needed for repair and rebuilding (25, 26). The scientific literature documents the need for a wide range of minerals that are vital to maintaining strong, healthy bones.
Calcium and other minerals are best not taken with fiber, because fiber can interfere with their absorption (1-5). There is evidence that calcium from supplements and dairy foods may inhibit iron absorption, although it has been very difficult to distinguish between the effects of calcium on iron absorption versus other inhibitory factors such as phytate (27).
Therefore, if you are iron deficient, it may be best to avoid taking calcium with meals (28). Calcium supplements are best administered at dinner and/or bedtime. They should always be taken with a full glass of water, juice, or other liquid to enhance solubility (29). If calcium-containing formulas are taken only once daily they may be best taken in the evening (30)
A problem overlooked by most doctors is that loss of bone density is associated with deficiencies of not just calcium, but a host of other nutrients including magnesium and vitamin D3 (31-37). In order for calcium to prevent bone loss, adequate amounts of vitamin D3, zinc, manganese and other nutrients should be available so that calcium, magnesium, and phosphorus can be incorporated into the bone matrix (38-46). Another issue that many people are not aware of is that many forms of calcium do not absorb particularly well (47,48).
Mineral Formula for Women reflects the need of women for more calcium than men. This product should be taken as an addition to Life Extension Mix™. Vitamin D is included to aid in calcium absorption and utilization.
References
1. J Nutr. 1992 Mar;122(3):442-9.
2. Proc Soc Exp Biol Med. 1985 Dec;180(3):432-46.
3. Am J Clin Nutr. 1983 Jul;38(1):12-9.
4. Am J Clin Nutr. 1979 Sep;32(9):1876-80.
5. Lancet. 1973 Feb 10;1(7798):283-8.
6. N Engl J Med. 1985 Jul 11;313(2):70-3.
7. Am J Ther. 1999 Nov;6(6):313-21.
8. J Am Coll Nutr. 1990 Dec;9(6):583-7.
9. J Bone Miner Res. 1988 Jun;3(3):253-8.
10. J Clin Endocrinol Metab. 1985 Aug;61(2):391-3.
11. JAMA. 1996 Apr 3;275(13):1016-22.
12. FASEB J. 2000 Jun;14(9):1132-8.
13. J Am Coll Nutr. 2000 Nov-Dec;19(6):754-60.
14. Int J Obes Relat Metab Disord. 2001 Apr;25(4):559-66.
15. FASEB J. 2001 Feb;15(2):291-3.
16. J Bone Miner Res. 1998 Apr;13(4):749-58.
17. Am J Clin Nutr 1987;45:1305-12.
18. Clinica Chimica Acta 2000;294:1-26.
19. Ann Pharmacother. 2002 Feb;36(2):255-60.
20. Br J Sports Med. 2006 Sep;40(9):773-8.
21. Congest Heart Fail. 2006 Jan-Feb;12(1):9-13
22. Am Heart J. 1984 Jul;108(1):188-93.
23. Angiology. 1994 Jul;45(7):637-45.
24. Magnes Res. 2006 Jun;19(2):113-22.
25. Nutr Rev. 1995 Sep;53(9 Pt 2):S23-S27.
26. J Clin Endocrinol Metab. 1998 Aug;83(8):2742-8.
27. Institute of Medicine Washington, DC: National Academy Press, 2001.
28. Am J Clin Nutr. 1991 Jan;53(1):106-11.
29. Public Health Rep. 1989 Sep-Oct;104 Suppl:46-50.
30. J Clin Endocrinol Metab. 1994 Sep;79(3):730-5.
31. Magnes Trace Elem. 1990;9(2):61-9.
32. Curr Pharm Des. 2003;9(32):2687-704.
33. Biol Trace Elem Res. 28:243-55, 1991.
34. Magnes Res. 1993 Jun;6(2):155-63.
35. J Reprod Med. 1990 May;35(5):503-7.
36. Gynecol Endocrinol. 1994 Mar;8(1):55-8.
37. J Clin Endocrinol Metab. 2006 Dec;91(12):4866-72
38. Eur J Obstet Gynecol Reprod Biol. 2000 May;90(1):97-101.
39. Arch Tierernahr. 1992;42(1):25-35.
40. Sci News. 1986; Sept. 27:199
41. J Am Coll Nutr. 1993;12:384-389
42. Orhtopedics. 1974;103:212-234
43. Acta Orthop Scand. 1977 May;48(1):1-4.
44. Acta Med Scand. 1980;207(1-2):67-70.
45. J Nutr. 1994 Jul;124(7):1060-4.
46. Crit Care Nurs Q. 2004 Jan-Mar;27(1):96-100.
47. Altern Med Rev. 1999 Apr;4(2):74-85.
48. Calcif Tissue Int. 1990 May;46(5):300-4.
Supplement Facts
Serving Size 1 capsule
Servings Per Container 100
Amount Per Serving
Vitamin D (as cholecalciferol) 100 IU
Calcium (as calcium citrate, malate, and succinate) 123 mg
Magnesium 100 mg
Manganese (as manganese gluconate) 0.25 mg
Potassium (as potassium aspartate) 8.05 mg
Other ingredients: gelatin, vegetable stearate, rice flour.
Contains corn and rice.
This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, or gluten. Contains NO artificial sweeteners, flavors, colors, or preservatives.
Dosage and Use
Take one capsule one to four times daily with or without food, or as recommended by a healthcare practitioner.
Total intake of calcium greater than 2000 mg per day provides no added benefit to bone health.
Warnings
Keep out of reach of children.
Do not exceed recommended dose.
Do not purchase if outer seal is broken or damaged.
If you have a bad reaction to product discontinue use immediately.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
